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Head, Sustainable CMC and Innovation

Cambridge, Massachusetts

Cambridge, Massachusetts| Fujisawa, Japan

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  • Job Type: Full Time
  • Job Level: Senior
  • Travel: 5-10%

The Pharmaceutical Sciences (Pharm Sci) organization is an integral part of global R&D at Takeda, translating science into therapeutic products for patients. When you join Pharm Sci, you become part of a team dedicated to bringing our products to life for our patients through innovation, dedication and talent while minimizing environmental impact.

We work as a member of Takeda’s Global Program Team (GPT) and take full ownership of Chemistry, Manufacturing & Control (CMC) activities — driving product development from bench to bedside.

The Pharm Sci team focuses on executing and enhancing business processes and partnering with key stakeholders and industry leaders to boldly deliver an increasingly complex portfolio. Always looking through a sustainability lens to protect our planet, we are embracing new ways of working, excelling in our data and digital transformation, building differentiated capabilities (CMC Acceleration), delivering innovative medical devices, and advancing an inclusive, innovative culture.

It is an exciting time to be in Pharm Sci. Join our journey and change the lives of patients!

Job ID R0132538 Date posted 10/28/2024 Location Cambridge, Massachusetts

Cambridge, Massachusetts| Fujisawa, Japan

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Job Description

About the Role:

As the Head of Sustainable CMC and Innovation, you will lead the strategic integration of sustainability and digital innovation within the Chemistry, Manufacturing, and Controls (CMC) function. Your primary objective will be to champion our "In Silico first" approach and ensure sustainability is embedded across all CMC activities, from research through to commercial manufacturing. This role is crucial in driving Takeda's mission toward achieving net-zero goals, enhancing product development efficiency, and accelerating time to market. You will foster a forward-thinking culture that prioritizes scientific excellence, sustainability, innovation, and value-driven leadership.

How you will contribute:

  • As the Head of Sustainable CMC and Innovation, your contributions will span strategic leadership, team management, and cross-functional collaboration, all aimed at embedding sustainability and digital innovation into every facet of CMC processes. Your primary responsibility will be to lead the adoption of cutting-edge digital technologies and sustainable methodologies across the CMC function. This includes driving the integration of "In-Silico first" approaches to optimize research, development, and manufacturing processes, thereby reducing time, costs, and environmental impact.

  • You will oversee a diverse, interdisciplinary team that combines expertise in science, engineering, and digital technologies. This team will work collaboratively to pioneer new sustainable practices within CMC, ensuring that these innovations are seamlessly integrated into Takeda’s global operations. Your leadership will be critical in nurturing a culture of innovation and sustainability, where team members are encouraged to experiment, share ideas, and contribute to Takeda's sustainability goals.

  • In addition, you will be responsible for cultivating strong collaborations both within and outside the organization. This includes working closely with other departments, such as Research & Development (R&D), Global Manufacturing & Supply (GMS), and Quality (GQ), to ensure that sustainability initiatives are aligned with broader corporate objectives. Externally, you will establish and maintain relationships with industry partners, regulatory bodies, and sustainability-focused organizations to stay ahead of industry trends and incorporate best practices into Takeda’s operations.

  • A key part of your role will also involve talent development. You will design and implement training programs to build expertise in advanced modeling, simulation, and data analytics within your team and beyond, ensuring that Takeda remains at the forefront of digital and sustainable future pharmaceutical manufacturing. Your efforts in talent management will help position Takeda as an industry leader, attracting top talent and fostering a high-performance culture focused on innovation and continuous improvement.

  • Furthermore, you will play a pivotal role in advocating for sustainability at the corporate level, representing the CMC function in broader organizational sustainability initiatives. You will influence strategy and decision-making, ensuring that sustainability remains a core consideration in all product development and manufacturing processes. Your presentations to senior leadership and active participation in global initiatives will help shape the direction of Takeda’s sustainability efforts, reinforcing the company’s commitment to reducing its environmental footprint and achieving long-term sustainability goals.

Qualifications:

  • PhD in Chemical Engineering, Pharmaceutical Sciences, Biotechnology, or a related field with 10+ years of relevant industry experience with substantial experience in digital transformation and sustainability in pharmaceutical manufacturing

  • A proven track record in leading digital CMC initiatives, advanced modeling, and sustainability projects

  • Strong scientific leadership, talent development, and strategic planning skills are essential, along with the ability to influence internal teams and the broader industry

  • Alignment with Takeda's leadership behaviors and a deep understanding of CMC digital technologies and sustainability practices are critical to success in this role

More about us:

At Takeda, we are transforming patient care through the development of novel specialty pharmaceuticals and best in class patient support programs. Takeda is a patient-focused company that will inspire and empower you to grow through life-changing work.

Certified as a Global Top Employer, Takeda offers stimulating careers, encourages innovation, and strives for excellence in everything we do. We foster an inclusive, collaborative workplace, in which our teams are united by an unwavering commitment to deliver Better Health and a Brighter Future to people around the world.

Empowering Our People to Shine

Learn more at takedajobs.com.

No Phone Calls or Recruiters Please.

Takeda Compensation and Benefits Summary

We understand compensation is an important factor as you consider the next step in your career. We are committed to equitable pay for all employees, and we strive to be more transparent with our pay practices.

For Location:

Cambridge, MA

U.S. Base Salary Range:

$169,400.00 - $266,200.00

The estimated salary range reflects an anticipated range for this position. The actual base salary offered may depend on a variety of factors, including the qualifications of the individual applicant for the position, years of relevant experience, specific and unique skills, level of education attained, certifications or other professional licenses held, and the location in which the applicant lives and/or from which they will be performing the job.The actual base salary offered will be in accordance with state or local minimum wage requirements for the job location.

U.S. based employees may be eligible for short-term and/or long-termincentives. U.S.based employees may be eligible to participate in medical, dental, vision insurance, a 401(k) plan and company match, short-term and long-term disability coverage, basic life insurance, a tuition reimbursement program, paid volunteer time off, company holidays, and well-being benefits, among others. U.S.based employees are also eligible to receive, per calendar year, up to 80 hours of sick time, and new hires are eligible to accrue up to 120 hours of paid vacation.

EEO Statement

Takeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law.

Locations

Cambridge, MA

JPN - Kanagawa - iPark

Worker Type

Employee

Worker Sub-Type

Regular

Time Type

Full time
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Where you fit in

Our teams are experienced in medicinal chemistry, multi-step synthesis, multimodal genetics, genomics datasets, pharmacokinetics and more. So wherever your expertise and passion lie, your work will have tangible outcomes, advancing an innovative pipeline that serves unmet needs.

We're delving deeper than ever inside the human body and its microbiome, implementing innovative approaches to deliver high-quality products that treat a range of illnesses, including IBD and cancer.

In our diverse, forward-thinking culture, we're constantly embracing new ways of working:

  • Partnering with research teams, GPTs, business development and our commercial partners in GMS/GQ
  • Supporting all stages of pre-clinical and clinical development
  • Providing enabling technologies, including formulation and delivery strategies, analytical expertise and IP
  • Developing processes to manufacture high-quality Clinical Trial Material and other
  • Focusing on broad therapeutic areas on multiple device platforms: Advanced Delivery Devices, Home & Point-Of-Care Diagnostics, Software & Connectivity for eHealth devices and state-of-the-art Medical Devices & Combination Products

On our team in Pharmaceutical Sciences, you’ll notice a big difference in your own life, too. You’ll be supported to develop your career. You'll connect with brilliant minds and be recognized for your accomplishments. Your curiosity, skills and dedication will have a place and a purpose. So even when you’re exploring the smallest of details, your world will be bigger than ever.

  • Perform cell processing operations

  • Support clean room activities

  • Ensure equipment maintenance

  • Support investigations in deviations

Along with incredibly passionate colleagues, there’s a clear commitment to invest in the best facilities and the right equipment needed to successfully perform world-class science.
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The heart of our work

Leading with innovation

Our pipeline

Our internal research capabilities and external partnerships contribute to an R&D engine that has produced exciting new molecular entities (NMEs) across our core Therapeutic Areas. Check out our pipeline and see how we’ll continue delivering a steady stream of next-generation therapies.

Learn more

What we believe in

Our values of Takeda-ism are Integrity, Fairness, Honesty and Perseverance, with Integrity as the core. These are brought to life through actions based on Patient, Trust, Reputation and Business, in that order.

Our belief in putting people first extends beyond our patients — it includes their families and communities, as well as our Takeda colleagues and their families.

We are committed to embracing our differences, valuing different perspectives, and fostering a culture of respect, inclusiveness and empowerment.

Our embedded Diversity, Equity & Inclusion (DE&I) strategy enables us to attract and retain exceptional talent, drives innovation, and helps address systemic inequalities in our communities.

  • Integrity

  • Fairness

  • Honesty

  • Perseverance

Working at Takeda

  • Inclusion

    Here, you will feel welcomed, respected, and valued as a vital contributor to our global team.
  • Collaboration

    A strong, borderless team, we strive together towards our priorities and inspiring mission.
  • Innovation

    Bold initiatives, continuous improvement, and creativity are at the heart of how we bring scientific breakthroughs from the lab to patients.
  • Top Workplace

    Recognized for our culture and way of working, we’re one of only 17 companies to receive Top Global Employer® status for 2024.
  • Work-Life

    Our people-first mission extends beyond patients to include their families, communities, and our own Takeda family.
  • Empowerment

    Through trust and respect, you will have genuine support from leaders, managers, and colleagues to do your best work.

We're Steadfast In Our Commitment to Four Key Imperatives

Patient


Responsibly translate science into highly innovative medicines and accelerate access to improve lives worldwide.

People


Create an exceptional people experience.

Planet


Protect our planet.

Data & Digital


Transform Takeda into the most trusted, data-driven, outcomes-based biopharmaceutical company.

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